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miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase

BACKGROUND: Currently, O6-methylguanine-DNA methyltransferase(MGMT) promoter methylation is the most convincing predictive biomarker for temozolomide (TMZ) response in patients with glioblastoma multiforme (GBM). However, technical obstacles prevent this biomarker from being applied widely. On the o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Transl Med
मुख्य लेखकों: Chen, Huiyuan, Li, Xinyi, Li, Wenbin, Zheng, Huyong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345002/
https://ncbi.nlm.nih.gov/pubmed/25890369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0435-y
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