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Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplex

BACKGROUND: We investigated how the synthesis of cAMP, stimulated by isoproterenol acting through β-adrenoreceptors and Gs, is strongly amplified by simultaneous incubation with baclofen. Baclofen is an agonist of δ-aminobutyric acid type B receptors [GABA(B)], known to inhibit adenylyl cyclase via...

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Detalhes bibliográficos
Publicado no:BMC Cell Biol
Main Authors: Robichon, Alain, Tinette, Sylvette, Courtial, Cédric, Pelletier, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15189569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-5-25
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