MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain

MutY homolog (MUTYH) excises adenine opposite 8-oxoguanine (8-oxoG) in DNA, thus preventing occurrence of G:C to T:A transversion. In cell-free extract prepared from the thymocytes of wild type but not MUTYH-null mice, adenine opposite 8-oxoG in DNA was excised by MUTYH, however, the generated apuri...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tominaga, Yohei, Ushijima, Yasuhiro, Tsuchimoto, Daisuke, Mishima, Masaki, Shirakawa, Masahiro, Hirano, Seiki, Sakumi, Kunihiko, Nakabeppu, Yusaku
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC434447/
https://ncbi.nlm.nih.gov/pubmed/15199168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh642
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky