Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.

Normal p53 function is required for optimal arrest of cells in the G1 phase of the cell cycle following certain types of DNA damage. Loss of this cell cycle checkpoint may contribute to tumor development by increasing the number of genetic abnormalities in daughter cells following DNA damage. The MD...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chen, C Y, Oliner, J D, Zhan, Q, Fornace, A J, Vogelstein, B, Kastan, M B
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC43434/
https://ncbi.nlm.nih.gov/pubmed/8146175
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki