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The MDM2-p53 pathway revisited

The p53 tumor suppressor is a key transcription factor regulating cellular pathways such as DNA repair, cell cycle, apoptosis, angiogenesis, and senescence. It acts as an important defense mechanism against cancer onset and progression, and is negatively regulated by interaction with the oncoprotein...

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Bibliografske podrobnosti
Main Authors: Nag, Subhasree, Qin, Jiangjiang, Srivenugopal, Kalkunte S., Wang, Minghai, Zhang, Ruiwen
Format: Artigo
Jezik:Inglês
Izdano: Editorial Department of Journal of Biomedical Research 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721034/
https://ncbi.nlm.nih.gov/pubmed/23885265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.27.20130030
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