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The MDM2-p53 pathway revisited
The p53 tumor suppressor is a key transcription factor regulating cellular pathways such as DNA repair, cell cycle, apoptosis, angiogenesis, and senescence. It acts as an important defense mechanism against cancer onset and progression, and is negatively regulated by interaction with the oncoprotein...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Editorial Department of Journal of Biomedical Research
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721034/ https://ncbi.nlm.nih.gov/pubmed/23885265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.27.20130030 |
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