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YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation

The Hippo pathway is an evolutionarily conserved regulator of normal and oncogenic growth. Engagement of Hippo pathway signaling results in the inactivation of the transcriptional coactivator YAP by preventing its nuclear entry. The mechanisms underlying the oncogenic properties of YAP remain incomp...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Tang, Eric D., Wang, Cun-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343196/
https://ncbi.nlm.nih.gov/pubmed/25636199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.01.011
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