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YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation
The Hippo pathway is an evolutionarily conserved regulator of normal and oncogenic growth. Engagement of Hippo pathway signaling results in the inactivation of the transcriptional coactivator YAP by preventing its nuclear entry. The mechanisms underlying the oncogenic properties of YAP remain incomp...
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Publicado no: | Cell Signal |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4343196/ https://ncbi.nlm.nih.gov/pubmed/25636199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.01.011 |
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