Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus

We sought to test whether vaccine-induced immune responses could protect rhesus macaques (RMs) against upfront heterologous challenges with an R5 simian-human immunodeficiency virus, SHIV-2873Nip. This SHIV strain exhibits many properties of transmitted HIV-1, such as tier 2 phenotype (relatively di...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Lakhashe, Samir K., Byrareddy, Siddappa N., Zhou, Mingkui, Bachler, Barbara C., Hemashettar, Girish, Hu, Shiu-Lok, Villinger, Francois, Else, James G., Stock, Shannon, Lee, Sandra J., Vargas-Inchaustegui, Diego A., Cofano, Egidio Brocca, Robert-Guroff, Marjorie, Johnson, Welkin E., Polonis, Victoria R., Forthal, Donald N., Loret, Erwann P., Rasmussen, Robert A., Ruprecht, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343195/
https://ncbi.nlm.nih.gov/pubmed/25245933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.08.065
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