Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells

Breast cancer type 1 susceptibility protein (BRCA1) has a multitude of functions that contribute to genome integrity and tumor suppression. Its participation in the repair of DNA double-strand breaks (DSBs) during homologous recombination (HR) is well recognized, whereas its involvement in the secon...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Björkman, Andrea, Qvist, Per, Du, Likun, Bartish, Margarita, Zaravinos, Apostolos, Georgiou, Konstantinos, Børglum, Anders D., Gatti, Richard A., Törngren, Therese, Pan-Hammarström, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343177/
https://ncbi.nlm.nih.gov/pubmed/25646469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418947112
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