TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia and dysregulation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contributing event in the pathogenesis of the aggressive form of this disease based on transgenic mouse studies. To determine a role of microRNAs on th...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Balatti, Veronica, Rizzotto, Lara, Miller, Cecelia, Palamarchuk, Alexey, Fadda, Paolo, Pandolfo, Rosantony, Rassenti, Laura Z., Hertlein, Erin, Ruppert, Amy S., Lozanski, Arletta, Lozanski, Gerard, Kipps, Thomas J., Byrd, John C., Croce, Carlo M., Pekarsky, Yuri
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343115/
https://ncbi.nlm.nih.gov/pubmed/25646413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500010112
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