Silencing profilin-1 inhibits gastric cancer progression via integrin β1/focal adhesion kinase pathway modulation

AIM: To investigate the role of profilin-1 (PFN1) in gastric cancer and the underlying mechanisms. METHODS: Immunohistochemical analysis, quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot were performed to detect PFN1 expression in clinical gastric carcinoma and adjacent ti...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Cheng, Ya-Jun, Zhu, Zhen-Xin, Zhou, Jian-Sheng, Hu, Zun-Qi, Zhang, Jian-Peng, Cai, Qing-Ping, Wang, Liang-Hua
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2015
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342907/
https://ncbi.nlm.nih.gov/pubmed/25741138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i8.2323
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