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Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors

Breast cancer patients who are HER2-positive receive targeted inhibitors to HER2, including trastuzumab and lapatinib. While patients benefit from the use of HER2 inhibitors, many fail therapy and almost all patients become resistant to treatment, indicating a critical need to prevent treatment fail...

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Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Yeh, Elizabeth S., Abt, Melissa A., Hill, Elizabeth G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342830/
https://ncbi.nlm.nih.gov/pubmed/25515931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3227-9
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