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Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors

Breast cancer patients who are HER2-positive receive targeted inhibitors to HER2, including trastuzumab and lapatinib. While patients benefit from the use of HER2 inhibitors, many fail therapy and almost all patients become resistant to treatment, indicating a critical need to prevent treatment fail...

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Bibliografiske detaljer
Udgivet i:Breast Cancer Res Treat
Main Authors: Yeh, Elizabeth S., Abt, Melissa A., Hill, Elizabeth G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342830/
https://ncbi.nlm.nih.gov/pubmed/25515931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3227-9
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