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Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer

Strategies for successful primary treatment of HER2-positive breast cancer include use of the HER2 inhibitors trastuzumab or lapatinib in combination with standard chemotherapy. While successful, many patients develop resistance to these HER2 inhibitors indicating an unmet need. Consequently, curren...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Phelps-Polirer, Kendall, Abt, Melissa A., Smith, Danzell, Yeh, Elizabeth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821489/
https://ncbi.nlm.nih.gov/pubmed/27045589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153025
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