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The Get1/2 Transmembrane Complex is an ER Membrane Protein Insertase
Hundreds of tail-anchored (TA) proteins, including SNAREs involved in vesicle fusion, are inserted post-translationally into the endoplasmic reticulum (ER) membrane by a dedicated protein targeting pathway(1–4). Prior to insertion, the C-terminal transmembrane domains (TMDs) of TA proteins are shiel...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342754/ https://ncbi.nlm.nih.gov/pubmed/25043001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13471 |
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