S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness

Activation of sphingosine-1-phosphate receptor 1 (S1PR1) plays a key role in repairing endothelial barrier function. We addressed the role of phosphorylation of the three intracellular tyrosine residues of S1PR1 in endothelial cells in regulating the receptor responsiveness and endothelial barrier f...

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Опубликовано в: :J Cell Sci
Главные авторы: Chavez, Alejandra, Schmidt, Tracy Thennes, Yazbeck, Pascal, Rajput, Charu, Desai, Bhushan, Sukriti, Sukriti, Giantsos-Adams, Kristina, Knezevic, Nebojsa, Malik, Asrar B., Mehta, Dolly
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342577/
https://ncbi.nlm.nih.gov/pubmed/25588843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.154476
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