A Cyclooxygenase-2-dependent Prostaglandin E(2) Biosynthetic System in the Golgi Apparatus

Cyclooxygenases (COXs) catalyze the committed step in prostaglandin (PG) biosynthesis. COX-1 is constitutively expressed and stable, whereas COX-2 is inducible and short lived. COX-2 is degraded via endoplasmic reticulum (ER)-associated degradation (ERAD) following post-translational glycosylation o...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yuan, Chong, Smith, William L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342474/
https://ncbi.nlm.nih.gov/pubmed/25548276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632463
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