Role of prostaglandin E(2)-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

Overexpression of human cyclooxygenase 2 (COX-2) in the mammary glands of transgenic mice induces tissue-specific tumorigenic transformation. However, the molecular mechanisms involved are not yet defined. Here we show that COX-2 expressed in the epithelial cell compartment regulates angiogenesis in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Chang, Sung-Hee, Liu, Catherine H., Conway, Rebecca, Han, David K., Nithipatikom, Kasem, Trifan, Ovidiu C., Lane, Timothy F., Hla, Timothy
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14688410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2535911100
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