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Role of prostaglandin E(2)-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
Overexpression of human cyclooxygenase 2 (COX-2) in the mammary glands of transgenic mice induces tissue-specific tumorigenic transformation. However, the molecular mechanisms involved are not yet defined. Here we show that COX-2 expressed in the epithelial cell compartment regulates angiogenesis in...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327192/ https://ncbi.nlm.nih.gov/pubmed/14688410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535911100 |
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