Role of prostaglandin E(2)-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

Overexpression of human cyclooxygenase 2 (COX-2) in the mammary glands of transgenic mice induces tissue-specific tumorigenic transformation. However, the molecular mechanisms involved are not yet defined. Here we show that COX-2 expressed in the epithelial cell compartment regulates angiogenesis in...

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Bibliografiske detaljer
Main Authors: Chang, Sung-Hee, Liu, Catherine H., Conway, Rebecca, Han, David K., Nithipatikom, Kasem, Trifan, Ovidiu C., Lane, Timothy F., Hla, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC327192/
https://ncbi.nlm.nih.gov/pubmed/14688410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535911100
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