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A Cyclooxygenase-2-dependent Prostaglandin E(2) Biosynthetic System in the Golgi Apparatus
Cyclooxygenases (COXs) catalyze the committed step in prostaglandin (PG) biosynthesis. COX-1 is constitutively expressed and stable, whereas COX-2 is inducible and short lived. COX-2 is degraded via endoplasmic reticulum (ER)-associated degradation (ERAD) following post-translational glycosylation o...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342474/ https://ncbi.nlm.nih.gov/pubmed/25548276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632463 |
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