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Proteolytic Regulation of Epithelial Sodium Channels by Urokinase Plasminogen Activator: CUTTING EDGE AND CLEAVAGE SITES

Plasminogen activator inhibitor 1 (PAI-1) level is extremely elevated in the edematous fluid of acutely injured lungs and pleurae. Elevated PAI-1 specifically inactivates pulmonary urokinase-type (uPA) and tissue-type plasminogen activators (tPA). We hypothesized that plasminogen activation and fibr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ji, Hong-Long, Zhao, Runzhen, Komissarov, Andrey A., Chang, Yongchang, Liu, Yongfeng, Matthay, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342445/
https://ncbi.nlm.nih.gov/pubmed/25555911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.623496
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