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Insulin Increases Cell Surface GLUT4 Levels by Dose Dependently Discharging GLUT4 into a Cell Surface Recycling Pathway

The insulin-responsive glucose transporter GLUT4 plays an essential role in glucose homeostasis. A novel assay was used to study GLUT4 trafficking in 3T3-L1 fibroblasts/preadipocytes and adipocytes. Whereas insulin stimulated GLUT4 translocation to the plasma membrane in both cell types, in nonstimu...

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Autors principals: Govers, Roland, Coster, Adelle C. F., James, David E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC434240/
https://ncbi.nlm.nih.gov/pubmed/15226445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.14.6456-6466.2004
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