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Fluorescence Study of Domain Structure and Lipid Interaction of Human Apolipoproteins E3 and E4
Human apolipoprotein E (apoE) isoforms exhibit different conformational stabilities and lipid-binding properties that give rise to altered cholesterol metabolism among the isoforms. Using Trp-substituted mutations and site-directed fluorescence labeling, we made a comprehensive comparison of the con...
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| Published in: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342298/ https://ncbi.nlm.nih.gov/pubmed/25281910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.09.019 |
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