Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I

As the principal component of high-density lipoprotein (HDL), apolipoprotein (apo) A-I plays essential roles in lipid transport and metabolism. Because of its intrinsic conformational plasticity and flexibility, the molecular details of the tertiary structure of lipid-free apoA-I have not been fully...

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Autores principales: Tanaka, Masafumi, Dhanasekaran, Padmaja, Nguyen, David, Nickel, Margaret, Takechi, Yuki, Lund-Katz, Sissel, Phillips, Michael C., Saito, Hiroyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003738/
https://ncbi.nlm.nih.gov/pubmed/21040803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2010.10.003
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