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Molecular Basis for the Differences in Lipid and Lipoprotein Binding Properties of Human Apolipoproteins E3 and E4
Human apolipoprotein (apo)E4 binds preferentially to very low density lipoproteins (VLDL) whereas apoE3 binds preferentially to high density lipoprotein (HDL), resulting in different plasma cholesterol levels with the two isoforms. To understand the molecular basis for this effect, the isolated apoE...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025481/ https://ncbi.nlm.nih.gov/pubmed/21114327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1017655 |
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