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IRF1 marks activated genes in SLE and can induce target gene expression
OBJECTIVE: IRF1 both mediates responses to type I interferons and the induction of interferons. It has been implicated in murine lupus models as a critical mediator of inflammation. A previous study of chromatin modifications in SLE patient monocytes implicated IRF1 as associated with increased hist...
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| Foilsithe in: | Arthritis Rheumatol |
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| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342285/ https://ncbi.nlm.nih.gov/pubmed/25418955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38964 |
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