The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

BACKGROUND: Gene expression studies of peripheral blood mononuclear cells from patients with systemic lupus erythematosus (SLE) have demonstrated a type I interferon signature and increased expression of inflammatory cytokine genes. Studies of patients with Aicardi Goutières syndrome, commonly cited...

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Main Authors: Shi, Lihua, Zhang, Zhe, Yu, Angela M., Wang, Wei, Wei, Zhi, Akhter, Ehtisham, Maurer, Kelly, Reis, Patrícia Costa, Song, Li, Petri, Michelle, Sullivan, Kathleen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010412/
https://ncbi.nlm.nih.gov/pubmed/24796678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093846
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