Endotoxin tolerance in monocytes can be mitigated by α2-interferon

Endotoxin tolerance is characterized by diminished expression of inflammatory cytokines after sequential exposure to Toll-like receptor stimuli. Many mechanisms contribute to tolerance; however, chromatin remodeling appears to be the most significant regulator. The type II interferon, IFN-γ, has bee...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Shi, Lihua, Song, Li, Maurer, Kelly, Sharp, James, Zhang, Zhe, Sullivan, Kathleen E.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2015
Subjects:
Host Defense & Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763867/
https://ncbi.nlm.nih.gov/pubmed/26206900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0914-450RR
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