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KINATEST-ID™: A PIPELINE TO DEVELOP PHOSPHORYLATION-DEPENDENT TERBIUM SENSITIZING KINASE ASSAYS

Non-receptor protein tyrosine kinases (NRTKs) are essential for cellular homeostasis, and thus are a major focus of current drug discovery efforts. Peptide substrates that can enhance lanthanide ion luminescence upon tyrosine phosphorylation enable rapid, sensitive screening of kinase activity, howe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Lipchik, Andrew M., Perez, Minervo, Bolton, Scott, Dumrongprechachan, Vasin, Ouellette, Steven B., Cui, Wei, Parker, Laurie L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342272/
https://ncbi.nlm.nih.gov/pubmed/25689372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja507164a
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