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KINATEST-ID™: A PIPELINE TO DEVELOP PHOSPHORYLATION-DEPENDENT TERBIUM SENSITIZING KINASE ASSAYS
Non-receptor protein tyrosine kinases (NRTKs) are essential for cellular homeostasis, and thus are a major focus of current drug discovery efforts. Peptide substrates that can enhance lanthanide ion luminescence upon tyrosine phosphorylation enable rapid, sensitive screening of kinase activity, howe...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342272/ https://ncbi.nlm.nih.gov/pubmed/25689372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja507164a |
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