Virus-Like Particles Activate Type I Interferon Pathways to Facilitate Post-Exposure Protection against Ebola Virus Infection

Ebola virus (EBOV) causes a severe hemorrhagic disease with high fatality. Virus-like particles (VLPs) are a promising vaccine candidate against EBOV. We recently showed that VLPs protect mice from lethal EBOV infection when given before or after viral infection. To elucidate pathways through which...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ayithan, Natarajan, Bradfute, Steven B., Anthony, Scott M., Stuthman, Kelly S., Bavari, Sina, Bray, Mike, Ozato, Keiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342244/
https://ncbi.nlm.nih.gov/pubmed/25719445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118345
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