Ebola Virus-Like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-Like Receptor and Interferon Signaling Pathways

Ebola viruses (EBOV) can cause severe hemorrhagic disease with high case fatality rates. Currently, no vaccines or therapeutics are approved for use in humans. Ebola virus-like particles (eVLP) comprising of virus protein (VP40), glycoprotein, and nucleoprotein protect rodents and nonhuman primates...

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Main Authors: Ayithan, Natarajan, Bradfute, Steven B., Anthony, Scott M., Stuthman, Kelly S., Dye, John M., Bavari, Sina, Bray, Mike, Ozato, Keiko
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
Assuntos:
Research Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924795/
https://ncbi.nlm.nih.gov/pubmed/24102579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0035
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