Ebola Virus-Like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-Like Receptor and Interferon Signaling Pathways

Ebola viruses (EBOV) can cause severe hemorrhagic disease with high case fatality rates. Currently, no vaccines or therapeutics are approved for use in humans. Ebola virus-like particles (eVLP) comprising of virus protein (VP40), glycoprotein, and nucleoprotein protect rodents and nonhuman primates...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ayithan, Natarajan, Bradfute, Steven B., Anthony, Scott M., Stuthman, Kelly S., Dye, John M., Bavari, Sina, Bray, Mike, Ozato, Keiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2014
Pynciau:
Research Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924795/
https://ncbi.nlm.nih.gov/pubmed/24102579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0035
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