Toll-Like Receptor Agonist Augments Virus-Like Particle-Mediated Protection from Ebola Virus with Transient Immune Activation

Identifying safe and effective adjuvants is critical for the advanced development of protein-based vaccines. Pattern recognition receptor (PRR) agonists are increasingly being explored as potential adjuvants, but there is concern that the efficacy of these molecules may be dependent on potentially d...

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Detalhes bibliográficos
Main Authors: Martins, Karen A. O., Steffens, Jesse T., van Tongeren, Sean A., Wells, Jay B., Bergeron, Alison A., Dickson, Samuel P., Dye, John M., Salazar, Andres M., Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933660/
https://ncbi.nlm.nih.gov/pubmed/24586996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089735
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