RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus

CRISPR-Cas is a prokaryotic adaptive immune system that provides sequence-specific defense against foreign nucleic acids. Here we report the structure and function of the effector complex of the Type III-A CRISPR-Cas system of Thermus thermophilus: the Csm complex (TtCsm). TtCsm is composed of five...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Staals, Raymond H. J., Zhu, Yifan, Taylor, David W., Kornfeld, Jack E., Sharma, Kundan, Barendregt, Arjan, Koehorst, Jasper J., Vlot, Marnix, Neupane, Nirajan, Varossieau, Koen, Sakamoto, Keiko, Suzuki, Takehiro, Dohmae, Naoshi, Yokoyama, Shigeyuki, Schaap, Peter J., Urlaub, Henning, Heck, Albert J. R., Nogales, Eva, Doudna, Jennifer A., Shinkai, Akeo, van der Oost, John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342149/
https://ncbi.nlm.nih.gov/pubmed/25457165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.10.005
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