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Distinct Functions for Aldh1 and Raldh2 in the Control of Ligand Production for Embryonic Retinoid Signaling Pathways

During vertebrate embryogenesis retinoic acid (RA) synthesis must be spatiotemporally regulated in order to appropriately stimulate various retinoid signaling pathways. Various forms of mammalian aldehyde dehydrogenase (ALDH) have been shown to oxidize the vitamin A precursor retinal to RA in vitro....

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Dettagli Bibliografici
Pubblicato in:Dev Genet
Autori principali: Haselbeck, Robert J., Hoffmann, Ines, Duester, Gregg
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342002/
https://ncbi.nlm.nih.gov/pubmed/10570467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1520-6408(1999)25:4<353::AID-DVG9>3.0.CO;2-G
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