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Distinct Functions for Aldh1 and Raldh2 in the Control of Ligand Production for Embryonic Retinoid Signaling Pathways

During vertebrate embryogenesis retinoic acid (RA) synthesis must be spatiotemporally regulated in order to appropriately stimulate various retinoid signaling pathways. Various forms of mammalian aldehyde dehydrogenase (ALDH) have been shown to oxidize the vitamin A precursor retinal to RA in vitro....

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Detalles Bibliográficos
Publicado en:Dev Genet
Main Authors: Haselbeck, Robert J., Hoffmann, Ines, Duester, Gregg
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342002/
https://ncbi.nlm.nih.gov/pubmed/10570467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1520-6408(1999)25:4<353::AID-DVG9>3.0.CO;2-G
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