Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina

Genetic studies have shown that retinoic acid (RA) signaling is required for mouse retina development, controlled in part by an RA-generating aldehyde dehydrogenase encoded by Aldh1a2 (Raldh2) expressed transiently in the optic vesicles. We examined the function of a related gene, Aldh1a1 (Raldh1),...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC164835/
https://ncbi.nlm.nih.gov/pubmed/12808103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4637-4648.2003
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