Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina

Genetic studies have shown that retinoic acid (RA) signaling is required for mouse retina development, controlled in part by an RA-generating aldehyde dehydrogenase encoded by Aldh1a2 (Raldh2) expressed transiently in the optic vesicles. We examined the function of a related gene, Aldh1a1 (Raldh1),...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 2003
נושאים:	Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4637-4648.2003
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