Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina

Genetic studies have shown that retinoic acid (RA) signaling is required for mouse retina development, controlled in part by an RA-generating aldehyde dehydrogenase encoded by Aldh1a2 (Raldh2) expressed transiently in the optic vesicles. We examined the function of a related gene, Aldh1a1 (Raldh1),...

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Bibliografische gegevens
Hoofdauteurs: Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164835/
https://ncbi.nlm.nih.gov/pubmed/12808103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4637-4648.2003
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