Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina

Genetic studies have shown that retinoic acid (RA) signaling is required for mouse retina development, controlled in part by an RA-generating aldehyde dehydrogenase encoded by Aldh1a2 (Raldh2) expressed transiently in the optic vesicles. We examined the function of a related gene, Aldh1a1 (Raldh1),...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4637-4648.2003
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