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Long-lived bone marrow plasma cells are induced early in response to T-cell independent or T-cell dependent antigens()

The signals required to generate long-lived plasma cells remain unresolved. One widely cited model posits that long-lived plasma cells derive from germinal centers (GCs) in response to T-cell dependent (TD) antigens. Thus, T-cell independent (TI) antigens, which fail to sustain GCs, are considered i...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bortnick, Alexandra, Chernova, Irene, Quinn, William J., Mugnier, Monica, Cancro, Michael P., Allman, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341991/
https://ncbi.nlm.nih.gov/pubmed/22529295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102808
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