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Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication by Niclosamide

Antiviral agents are urgently needed to fight severe acute respiratory syndrome (SARS). We showed that niclosamide, an existing antihelminthic drug, was able to inhibit replication of a newly discovered coronavirus, SARS-CoV; viral antigen synthesis was totally abolished at a niclosamide concentrati...

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Hlavní autoři: Wu, Chang-Jer, Jan, Jia-Tsrong, Chen, Chi-Min, Hsieh, Hsing-Pang, Hwang, Der-Ren, Liu, Hwan-Wun, Liu, Chiu-Yi, Huang, Hui-Wen, Chen, Su-Chin, Hong, Cheng-Fong, Lin, Ren-Kuo, Chao, Yu-Sheng, Hsu, John T. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC434198/
https://ncbi.nlm.nih.gov/pubmed/15215127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2693-2696.2004
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