Lucidone Suppresses Hepatitis C Virus Replication by Nrf2-Mediated Heme Oxygenase-1 Induction

Upon screening of plant-derived natural products against hepatitis C virus (HCV) in the replicon system, we demonstrate that lucidone, a phytocompound, isolated from the fruits of Lindera erythrocarpa Makino, significantly suppressed HCV RNA levels with 50% effective concentrations of 15 ± 0.5 μM an...

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Bibliografske podrobnosti
Main Authors: Chen, Wei-Chun, Wang, Sheng-Yang, Chiu, Chien-Chih, Tseng, Chin-Kai, Lin, Chun-Kuang, Wang, Hui-Chun, Lee, Jin-Ching
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591928/
https://ncbi.nlm.nih.gov/pubmed/23254429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02053-12
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