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Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway

Hepatitis C virus (HCV) infection-induced oxidative stress is a major risk factor for the development of HCV-associated liver disease. Sulforaphane (SFN) is an antioxidant phytocompound that acts against cellular oxidative stress and tumorigenesis. However, there is little known about its anti-viral...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Yu, Jung-Sheng, Chen, Wei-Chun, Tseng, Chin-Kai, Lin, Chun-Kuang, Hsu, Yao-Chin, Chen, Yen-Hsu, Lee, Jin-Ching
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811417/
https://ncbi.nlm.nih.gov/pubmed/27023634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152236
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