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Structure and Activity of Tryptophan-rich TSPO Translocator Proteins
TSPO translocator proteins bind steroids and porphyrins, and they are implicated in many human diseases, for which they serve as biomarkers and therapeutic targets. TSPOs have tryptophan-rich sequences that are fhighly conserved from bacteria to mammals. We report crystal structures for Bacillus cer...
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| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4341906/ https://ncbi.nlm.nih.gov/pubmed/25635100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa1534 |
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