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Structure and Activity of Tryptophan-rich TSPO Translocator Proteins
TSPO translocator proteins bind steroids and porphyrins, and they are implicated in many human diseases, for which they serve as biomarkers and therapeutic targets. TSPOs have tryptophan-rich sequences that are fhighly conserved from bacteria to mammals. We report crystal structures for Bacillus cer...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4341906/ https://ncbi.nlm.nih.gov/pubmed/25635100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa1534 |
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