Model System for High-Throughput Screening of Novel Human Immunodeficiency Virus Protease Inhibitors in Escherichia coli

Novel human immunodeficiency virus (HIV) protease inhibitors are urgently needed for combating the drug-resistance problem in the fight against AIDS. To facilitate lead discovery of HIV protease inhibitors, we have developed a safe, convenient, and cost-effective Escherichia coli-based assay system....

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Bibliographic Details
Main Authors: Cheng, Ting-Jen, Brik, Ashraf, Wong, Chi-Huey, Kan, Chen-Chen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434161/
https://ncbi.nlm.nih.gov/pubmed/15215092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2437-2447.2004
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