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Rethinking gene regulatory networks in light of alternative splicing, intrinsically disordered protein domains, and post-translational modifications

Models for genetic regulation and cell fate specification characteristically assume that gene regulatory networks (GRNs) are essentially deterministic and exhibit multiple stable states specifying alternative, but pre-figured cell fates. Mounting evidence shows, however, that most eukaryotic precurs...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Dev Biol
Asıl Yazarlar: Niklas, Karl J., Bondos, Sarah E., Dunker, A. Keith, Newman, Stuart A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341551/
https://ncbi.nlm.nih.gov/pubmed/25767796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00008
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