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High yield purification of full-length functional hERG K(+) channels produced in Saccharomyces cerevisiae
The hERG potassium channel is essential for repolarization of the cardiac action potential. Due to this vital function, absence of unintended and potentially life-threatening interactions with hERG is required for approval of new drugs. The structure of hERG is therefore one of the most sought-after...
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| Publicado no: | Microb Cell Fact |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4341239/ https://ncbi.nlm.nih.gov/pubmed/25656388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0193-9 |
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