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Fast and accurate site frequency spectrum estimation from low coverage sequence data

Motivation: The distribution of allele frequencies across polymorphic sites, also known as the site frequency spectrum (SFS), is of primary interest in population genetics. It is a complete summary of sequence variation at unlinked sites and more generally, its shape reflects underlying population g...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Han, Eunjung, Sinsheimer, Janet S., Novembre, John
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341071/
https://ncbi.nlm.nih.gov/pubmed/25359894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu725
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