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Replication of Herpes Simplex Virus 1 Depends on the γ(1)34.5 Functions That Facilitate Virus Response to Interferon and Egress in the Different Stages of Productive Infection
The ability of the γ(1)34.5 protein to suppress the PKR response plays a crucial role in herpes simplex virus pathogenesis. In this process, the γ(1)34.5 protein associates with protein phosphatase 1 to form a large complex that dephosphorylates eIF-2α and thereby prevents translation shutoff mediat...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434106/ https://ncbi.nlm.nih.gov/pubmed/15220440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7653-7666.2004 |
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