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Replication of Herpes Simplex Virus 1 Depends on the γ(1)34.5 Functions That Facilitate Virus Response to Interferon and Egress in the Different Stages of Productive Infection

The ability of the γ(1)34.5 protein to suppress the PKR response plays a crucial role in herpes simplex virus pathogenesis. In this process, the γ(1)34.5 protein associates with protein phosphatase 1 to form a large complex that dephosphorylates eIF-2α and thereby prevents translation shutoff mediat...

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Hlavní autoři: Jing, Xianghong, Cerveny, Melissa, Yang, Kui, He, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC434106/
https://ncbi.nlm.nih.gov/pubmed/15220440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7653-7666.2004
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